Evidence for the intracardiovascular hyperclotting state induced by atrial fibrillation itself

Nonvalvular atrial fibrillation: evidence for a prothrombotic state.

OBJECTIVE To determine whether patients with nonvalvular atrial fibrillation (NVAF) have prothrombotic changes compared with patients in sinus rhythm. DESIGN Cross-sectional study. Hemostatic function compared in NVAF patients without prior embolic event (transient ischemic attack or embolic stroke) and control subjects without prior thrombotic stroke, and in NVAF patients with prior embolic ...

Remodeling Induced by Atrial Fibrillation

trial fibrillation (AF) is one of the most common arrhythmias observed in clinical practice. It is well known that paroxysms of AF become longer, that AF becomes refractory to pharmacological rhythm-control treatment, and that the electrical defibrillation threshold is gradually elevated. The most accepted concept explaining these clinical phenomena is so-called remodeling. There is a body of e...

by ibuprofen overdose . Atrial fibrillation induced

Sir, I read with interest the case report of Shalev et al.} on falciparum malaria-induced hypoglycaemia, and I wish to suggest another possible and important mechanism in the pathogenesis of hypoglycaemia associated with falciparum malaria infection. Several recent studies have demonstrated elevated serum levels of tumour necrosis factor-a (TNF) in patients with falciparum malaria,2-6 where thi...

Atrial fibrillation begets atrial fibrillation: autonomic mechanism for atrial electrical remodeling induced by short-term rapid atrial pacing.

BACKGROUND The mechanism(s) for acute changes in electrophysiological properties of the atria during rapid pacing induced atrial fibrillation (AF) is not completely understood. We sought to evaluate the contribution of the intrinsic cardiac autonomic nervous system in acute atrial electrical remodeling and AF induced by 6-hour rapid atrial pacing. METHODS AND RESULTS Continuous rapid pacing (...

Adenosine-Induced Atrial Fibrillation